Effect of amphotericin B on capsule and cell size in Cryptococcus neoformans during murine infection.
نویسندگان
چکیده
Antifungal drugs can affect the cellular morphology of Cryptococcus neoformans in culture, which alters its interactions with phagocytes. We examined the effects of amphotericin B on C. neoformans during murine infection. The antifungal reduced capsule size and serum polysaccharide, which suggests an additional mechanism for amphotericin B's efficacy in cryptococcosis.
منابع مشابه
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 49 10 شماره
صفحات -
تاریخ انتشار 2005